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Mutations in several genes may refine prognosis in normal karyotype AML.
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The management of an isolated core needle breast biopsy reading of lobular neoplasia (LN) is controversial. Although this finding is associated with an increased risk for cancer, the current belief is that it, itself, is not a pre-malignant lesion.
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Orchiectomy rates have increased and LHRH prescriptions have decreased over the past 5 years. Could this be related to Medicare reimbursement?
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In a Phase III randomized trial of adjuvant chemotherapy using the platinum-based PELF (platinum, etoposide, leucovorin, and fluorouracil) regimen after potentially curative surgery for gastric cancer, no significant improvement in disease-free or overall survival was observed. The findings are discussed in the context of other trials and highlight the uncertainty surrounding the appropriate approach for the treatment of patients in this setting.
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Pioglitazone and heart disease; ARBs manufacturers spend millions to show the non-inferiority of their products compared to less expensive, generic ACE inhibitors; some athletes turn to growth hormone because it is difficult to detect; FDA Actions
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This study of patients with PSP and MSA diagnosed at autopsy, 70% of whom were correctly diagnosed during their lifetime, suggests differences in disease subtypes that impact upon prognosis and response to treatment.
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Sleep deprivation increases the frequency of episodes in patients with known sleepwalking, and supports the theory that the condition arises during slow-wave sleep.
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Stenting is a possible option for the treatment of intracranial stenosis, but its safety and efficacy require further study in a randomized trial.
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